Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 35.00 | |
100 mg | In stock | $ 48.00 | |
200 mg | In stock | $ 59.00 | |
500 mg | In stock | $ 68.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers. |
Synonyms | KOE-1173 (hydrochloride), Mexiletine HCl, KO1173 |
Molecular Weight | 215.72 |
Formula | C11H18ClNO |
CAS No. | 5370-01-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (231.78 mM)
H2O: 21.6 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Mexiletine hydrochloride 5370-01-4 Immunology/Inflammation Membrane transporter/Ion channel Metabolism Sodium Channel AhR Na channels KO-1173 KOE 1173 KOE-1173 (hydrochloride) KOE-1173 antiarrhythmic Mexiletine Mexiletine HCl KO1173 Inhibitor KOE1173 ischemia Class IB myocardial inhibit KO 1173 Mexiletine Hydrochloride Na+ channels inhibitor